I am running 18x10.5 +43 with a 295 hankook with rolled fenders just fine. Yours should just extend about 2 mm further out. Only rubbing I had was when I lowered it a bit too much. It would only rub on hard bumps on the lip. Has since been resolved. Not running any crazy amount of camber.
Only good pictures I have this year of it with the 295's in the rear. Rant 275's last year and it was just too stretched for me.